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Entamoeba gingivalis, a parasitic pathogen (single-celled protozoan, amoeba) that occurs in the oral cavity of humans, computer illustration. E. gingivalis is an amoeba that can be found within the spaces of the teeth, gingival pockets (gums) or tonsils. This amoeba can cause periodontal disease and gingivitis. Note the broad lobopodia (pseudopodia) that are forming at the tips of the cell body. Pseudopods extend from the amoeba cell causing a slow gliding locomotion over substrate surfaces. E. gingivalis is similar to another human parasitic protozoan, Entamoeba histolytica.