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SV40 antigen and tumor suppressor - stock illustration

SV40 antigen and tumour suppressor. Molecular model of the simian virus (SV40) large T antigen bound to a retinoblastoma tumour suppressor (Rb). Large T antigens play a role in regulating the viral life cycle of the polyomaviridae viruses, such as SV40. SV40 is potentially tumour-causing in primates and humans. Rb proteins encourage normal cell cycles, thus preventing the formation of tumours. When the large T antigen binds to Rb, the tumour suppressor's action is blocked, and the development of malignant tumours becomes more likely.
SV40 antigen and tumour suppressor. Molecular model of the simian virus (SV40) large T antigen bound to a retinoblastoma tumour suppressor (Rb). Large T antigens play a role in regulating the viral life cycle of the polyomaviridae viruses, such as SV40. SV40 is potentially tumour-causing in primates and humans. Rb proteins encourage normal cell cycles, thus preventing the formation of tumours. When the large T antigen binds to Rb, the tumour suppressor's action is blocked, and the development of malignant tumours becomes more likely.
SV40 antigen and tumor suppressor
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